Research Assistant Position: Molecular Imaging

Research Assistant Position: Molecular Imaging
Prof. Pedro Brugarolas, Gordon Center for Medical Imaging at Massachusetts General Hospital, Harvard Medical School
spring, summer, and beyond


Description of the project and duties: The candidate will work alongside the PI and a postdoc producing and characterizing new radioactive small molecules for medical diagnostics. The goal of the lab is to develop new radiotracers for positron emission tomography (PET) and characterize them in animal models of disease. See Development of a PET tracer for potassium channels to image demyelination for an example of the work. Requirements: 1 semester of general chemistry with lab. Desired: 1 semester of organic chemistry with lab. Previous research experience in a chemistry or biochemistry lab. Additional Information: Term and hours are negotiable. Preference will be given to students interested in working 12+ months to allow them to master techniques and produce results. During summers, students are encouraged to spend 25+ hours a week in the lab. During the school year, students are encouraged to attend lab meetings and spend time in the lab as their schedule permits (minimum 8h/week). The lab is located at Mass General Hospital, Bulfinch 051, 55 Fruit Street in Boston. Additional lab information is available at the lab website and the department website. Learning outcome: Students will learn the fundamentals of radiochemistry and PET imaging. Students will learn how to work safely in a radiochemistry lab. Students will also learn methods to generate and characterize small molecules including HPLC, NMR, etc. Mentoring: Students will work alongside a postdoc (1 student per postdoc). As they become proficient in certain tasks, students will gain independence. Students may not work alone in the lab. Postdoc will provide day-to-day supervision. PI will meet with the student regularly (once or twice a week) to review progress and assist with the research experiments. Funding: Students are encouraged to apply to the HCRP and other fellowships or register for a research course credit. Limited funding may be available from the lab. To Apply: Please send CV/resume and interests to Dr. Pedro Brugarolas at pbrugarolas@mgh.harvard.edu. (posted 4/2018)