Christian A. Webb

Dr. Webb’s Treatment and Etiology of Depression in Youth (TEDY) Laboratory uses a multimodal approach (EEG, fMRI, experience sampling, passive smartphone sensor data, laboratory-based experiments and clinical interviewing) to investigate the etiology and pathophysiology of depression in adolescents, as well as predictors and mechanisms of change in psychotherapeutic and pharmacological treatments for depression. Relevant to the pursuit of personalized medicine in psychiatry, Dr. Webb’s more recent research leverages machine learning to identify pretreatment predictors of symptom improvement in psychotherapeutic and pharmacological treatments for depression. Greater knowledge of variables predicting better or worse treatment response prior to the start of treatment may have important clinical implications regarding which interventions are best suited for whom, thus informing treatment selection.