S. Barak Caine
Associate Professor of Psychology, HMS
Much of my work is aimed at evaluating the roles of distinct monoamine transporters and receptor subtypes in the psychomotor and abuse-related effects of cocaine and amphetamine. A primary goal is to assess the potential of novel compounds as candidate medications for the treatment of psychosis (e.g., schizophrenia) or as pharmacological adjuncts for the treatment of cocaine abuse and dependence. Behavioral pharmacology is used to evaluate pharmacological mechanisms underlying the psychomotor stimulant, sensorimotor disruptive, discriminative stimulus and reinforcing effects of cocaine and related drugs.