Director: Translational Psychiatry Laboratory
Harvard Medical School, McLean Hospital
Dr. Balu and his Translational Psychiatry Laboratory use a wide array of cutting-edge tools (i.e., mouse genetics and viral techniques, biochemistry, molecular biology, immunohistochemistry, and behavior) to understand the neurobiological mechanisms that underlie the synaptic and behavioral abnormalities associated with psychiatric disorders, such as schizophrenia and post-traumatic stress disorder. Dr. Balu aims to use these insights into the pathophysiology of disease to test compounds for potential therapeutic efficacy in his models. His laboratory is also interested in how the same neurotransmitter systems that are dysregulated in psychiatric disorders are also affected in neurodegenerative disorders, like Alzheimer’s disease, as well as traumatic brain injury.